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The mean first passage time as a function of the reaction coordinate: the distance from the LF N-terminus along the channel axis to the ϕ-clamp in Angstroms. The color code is the same as in Fig. 2. The time is provided in a logarithmic scale. The top panel is the MFPT toward the ϕ-clamp from the channel mouth. The lower panel is the reverse process, from the ϕ-clamp to the mouth of the channel.
