Table II.
Summary statistics for the gene-based test of rare variants in the UCSF Family Alcoholism study
| CHR | BEGIN | END | GENE | Variant No. | P |
|---|---|---|---|---|---|
| 1 | 231762651 | 232172555 | DISC1 | 16 | 1.72E-01 |
| 1 | 154245225 | 154247908 | HAX1 | 3 | 2.80E-02 |
| 1 | 154542792 | 154548331 | CHRNB2 | 6 | 1.00E+00 |
| 3 | 54156747 | 55107846 | CACNA2D3 | 14 | 7.71E-01 |
| 6 | 29571342 | 29600126 | GABBR1 | 2 | 1.90E-01 |
| 8 | 12943795 | 13357567 | DLC1 | 29 | 7.29E-01 |
| 8 | 77895667 | 77913120 | PEX2 | 9 | 3.35E-01 |
| 9 | 18533279 | 18906866 | ADAMTSL1 | 20 | 1.00E+00 |
| 9 | 3828355 | 4286526 | GLIS3 | 20 | 3.00E-01 |
| 14 | 45369682 | 45374747 | C14ORF28 | 3 | 5.13E-01 |
| 14 | 45403373 | 45414662 | KLHL28 | 6 | 1.00E+00 |
| 15 | 78873272 | 78885473 | CHRNA5 | 3 | 5.33E-01 |
| 15 | 78885473 | 78911261 | CHRNA3 | 5 | 5.66E-01 |
| 15 | 78917316 | 79012516 | CHRNB4 | 10 | 3.96E-01 |
| 20 | 61978149 | 62005888 | CHRNA4 | 12 | 6.71E-01 |
CHR: chromosome; BEGIN: the start position of gene; END; the end position of gene; Variant No.: the valid available rare nonsynonymous variants. P: the EMMAX SKAT association P-value.