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. 2017 Oct 25;7:13991. doi: 10.1038/s41598-017-14451-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Annotation of novel lncRNAs. (a) The top ten significantly enriched KEGG pathways for protein-coding genes near novel lncRNAs. (b) The top five disease ontologies of protein-coding genes near novel lncRNAs. (c) Density histograms of pairwise Pearson expression correlations between genes of different classes in trans. (d) Density histograms of pairwise Pearson expression correlations between genes of different classes in cis. (e) The top ten significantly enriched pathways for mRNAs cis positively correlated with novel lncRNAs (Pearson correlation > 0.7).