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. 2017 Oct 25;7:14036. doi: 10.1038/s41598-017-14492-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Immunohistopathology of kidneys from adenine-fed rats. (A) Immunohistopathological expression of AQP1 and ED1. (B) Mesenchymal stem cells (MSCs) transplantation significantly increased the AQP1-positive area (P < 0.0001) and (C) reduced the ED1-positive area (P < 0.0005) as compared to the those in control group. Data are expressed as the mean ± SEM. Black scale bars: 500 μm, white scale bars: 100 μm.