Table 3.

General Linear Model analysis of the biomarkers in HC and AD at 18 and 54 month time points in non-converters only. Data are presented as Mean ± S.E., although statistical analysis was performed on the log₁₀ value to better approximate a normal distribution. For IL-5, IL-6 and IL-17 the log₁₀ conversion was performed on the (raw data + 1) in order to accommodate 0 values.

	HC 18	AD 18	p	HC 54	AD 54	p
EGF	27.33 ± 1.69	28.81 ± 6.52	0.48	16.41 ± 0.57	22.46 ± 2.48	0.08
IL12/23 p40	114.47 ± 2.88	119.81 ± 9.39	0.20	122.01 ± 3.59	143.64 ± 11.45	0.60
IL-15	1.96 ± 0.02	2.14 ± 0.07	0.11	2.26 ± 0.03	2.52 ± 0.08	0.21
IL-17	1.59 ± 0.10	1.82 ± 0.22	0.29	2.15 ± 0.46	2.20 ± 0.27	0.37
MCP-1	62.46 ± 0.88	70.99 ± 5.85	0.44	67.96 ± 1.06	76.37 ± 3.79	0.44
MMP-2	83561 ± 794	86564 ± 2690	0.78	89516 ± 894	94120 ± 3072	0.67
Eot-3	4.80 ± 0.67	8.47 ± 3.20	0.39	6.81 ± 2.84	7.72 ± 2.51	0.03
IL-5	0.74 ± 0.08	0.48 ± 0.05	0.26	0.67 ± 0.05	0.54 ± 0.06	0.61
IL-6	1.38 ± 0.30	1.39 ± 0.20	0.32	1.84 ± 0.42	1.59 ± 0.19	0.21
IL-7	0.99 ± 0.06	0.90 ± 0.11	0.76	0.64 ± 0.03	0.77 ± 0.06	0.16
IL-10	1.30 ± 0.14	1.05 ± 0.05	0.49	1.26 ± 0.11	1.44 ± 0.34	0.78
TARC	72.15 ± 5.26	77.68 ± 11.09	0.62	54.92 ± 2.94	68.64 ± 7.21	0.08
TNF-a	1.62 ± 0.03	1.86 ± 0.09	0.54	1.70 ± 0.03	2.11 ± 0.12	0.13
Ang-2	8031 ± 188	8553 ± 493	0.83	8897 ± 210	9592 ± 594	0.60
SCF	92.70 ± 1.24	92.63 ± 3.60	0.50	97.82 ± 1.42	101.21 ± 4.23	0.96
EGFR	34396 ± 311	33559 ± 785	0.43	34625 ± 301	32745 ± 809	0.71
Leptin	27930 ± 1787	29764 ± 4993	0.59	31358 ± 2131	43674 ± 7188	0.42
PYY	79.65 ± 1.98	103.06 ± 8.97	0.02	85.94 ± 2.34	106.69 ± 9.91	0.09