Table 8.

General Linear Model analysis of the biomarkers in HC according to brain amyloid deposition (PiB−, SUVR < 1.5 and PiB+, SUVR > 1.5) at 18 and 54 month time points. Data are presented as Mean ± S.E., although statistical analysis was performed on the log₁₀ value to better approximate a normal distribution. For IL-5, IL-6 and IL-17 the log₁₀ conversion was performed on the (raw data + 1) in order to accommodate 0 values.

	HC PiB− 18	HC PiB+ 18	p	HC PiB− 54	HC PiB+ 54	p
EGF	30.46 ± 3.38	25.37 ± 3.57	0.54	19.78 ± 2.00	18.10 ± 1.89	0.93
IL12/23 p40	104.81 ± 6.54	130.15 ± 24.06	0.11	105.67 ± 7.35	151.73 ± 24.61	0.023
IL-15	1.91 ± 0.06	1.97 ± 0.11	0.98	2.29 ± 0.08	2.34 ± 0.17	0.46
IL-17	1.44 ± 0.17	1.55 ± 0.32	0.91	1.80 ± 0.27	2.38 ± 1.02	0.90
MCP-1	66.24 ± 2.75	71.37 ± 4.47	0.16	70.27 ± 2.30	76.42 ± 4.03	0.33
MMP-2	81457 ± 1661	82594 ± 3356	0.54	87571 ± 2339	91574 ± 3226	0.57
Eot-3	5.08 ± 1.48	3.58 ± 0.47	0.46	5.36 ± 1.89	3.79 ± 0.44	0.93
IL-5	0.90 ± 0.22	0.65 ± 0.12	0.53	0.67 ± 0.12	0.67 ± 0.11	0.85
IL-6	1.11 ± 0.13	3.10 ± 1.90	0.48	1.06 ± 0.12	4.22 ± 2.45	0.29
IL-7	1.17 ± 0.12	0.94 ± 0.12	0.45	0.85 ± 0.12	0.74 ± 0.07	0.77
IL-10	1.20 ± 0.19	3.70 ± 2.40	0.13	1.01 ± 0.07	2.98 ± 1.78	0.15
TARC	69.29 ± 5.99	69.90 ± 6.93	0.72	57.89 ± 5.46	58.62 ± 6.98	0.72
TNF-a	1.60 ± 0.07	1.73 ± 0.13	0.81	1.59 ± 0.06	1.83 ± 0.13	0.57
Ang-2	7966 ± 461	8741 ± 660	0.64	7944 ± 374	8711 ± 614	0.74
SCF	94.56 ± 3.10	107.14 ± 5.04	0.26	101.14 ± 3.66	110.52 ± 5.53	0.99
EGFR	35064 ± 723	31726 ± 1285	0.18	36222 ± 773	33255 ± 1467	0.32
Leptin	34551 ± 6605	17707 ± 4844	0.24	34021 ± 6551	28271 ± 8892	0.35
PYY	76.69 ± 4.80	69.00 ± 5.98	0.55	85.58 ± 4.60	76.74 ± 8.81	0.54