Table 3.

Impact of anesthetic type on overall survival and RF survival

Outcome	Model	Hazard Ratio (95% CI)	P value
Overall survival	Unadjusted	1.50 (1.19–1.89)	0.001
	Multivariable adjusted*	1.58 (1.24–2.01)	<0.001
	PS matching†	1.45 (1.11–1.89)	0.006
	PS matching and adjusted by covariate‡	1.57 (1.19–2.07)	0.001
RF survival	Unadjusted	1.48 (1.18–1.86)	0.001
	Multivariable adjusted§	1.42 (1.12–1.79)	0.003
	PS matching†	1.44 (1.11–1.87)	0.006
	PS matching and adjusted by covariate‖	1.36 (1.04–1.77)	0.024

Hazard ratios are for the VA group relative to the TIVA group.

*Adjusted by age, body mass index, diabetes mellitus, preoperative chemo-radiation therapy, preoperative albumin levels, pathologic stage of cancer, pRBC given intraoperatively, and postoperative complications (myocardial dysfunction and sepsis).

†Cox proportional hazards model was applied by using propensity score-based matching with robust standard errors.

‡Adjusted by pathologic stage of cancer, pRBC given intraoperatively, and postoperative complications (myocardial dysfunction and sepsis).

§Adjusted by age, body mass index, preoperative chemo-radiation therapy, preoperative albumin levels, pathologic stage of cancer, and pRBC given intraoperatively.

‖Adjusted by pathologic stage of cancer, pRBC given intraoperatively, and postoperative chemo-radiation therapy.

RF = Recurrence-free; CI = confidence interval; PS = propensity score; VA = volatile inhalational anesthesia; TIVA = total intravenous anesthesia; pRBC = packed red blood cell.