Fig. 3.

Levels of LNG released from MZCL IVRs were not impacted by MZC. Levels of LNG in blood resulting from in vivo release from LNG and MZCL IVRs are shown. Arrows indicate times IVRs were inserted/exchanged. Open triangles represent LNG levels between 0.10 and 0.19 ng/ml. Open inverted triangles represent LNG levels between 0.09 and 0.10 ng/ml. The first SIV RNA positive time point for each animal is shown in red with red asterisks indicating that plasma virus RNA was only detected after challenges were concluded. Blue asterisks indicate times of noticeable vaginal bleeding