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. 2017 Jun 9;7(6):840–858. doi: 10.1007/s13346-017-0389-0

Table 3.

NNRTI-resistance profile of I178V

NNRTI EC50 (95% confidence interval)
SHIV-RT WT SHIV-RTEJ42 I178V HIV-1NL4-3 WT HIV-1NL4-3 I178V
MIV-150 1.1 (0.9–1.3) 1.1 (0.8–1.5) 0.96 (0.80–1.14) 0.70 (0.61–0.82)
Efavirenz ND ND 1.22 (1.05–1.42) 0.80 (0.66–0.96)
Etravirine 3.1 (2.5–3.8) 2.2 (1.3–3.5) 0.54 (0.42–0.68) 0.23 (0.18–0.29)
Rilpivirine 0.5 (0.4–0.7) 0.3 (0.2–0.4) 1.79 (1.48–2.16) 0.92 (0.70–1.21)

ND not determined