Table 3.
NNRTI | EC50 (95% confidence interval) | |||
---|---|---|---|---|
SHIV-RT WT | SHIV-RTEJ42 I178V | HIV-1NL4-3 WT | HIV-1NL4-3 I178V | |
MIV-150 | 1.1 (0.9–1.3) | 1.1 (0.8–1.5) | 0.96 (0.80–1.14) | 0.70 (0.61–0.82) |
Efavirenz | ND | ND | 1.22 (1.05–1.42) | 0.80 (0.66–0.96) |
Etravirine | 3.1 (2.5–3.8) | 2.2 (1.3–3.5) | 0.54 (0.42–0.68) | 0.23 (0.18–0.29) |
Rilpivirine | 0.5 (0.4–0.7) | 0.3 (0.2–0.4) | 1.79 (1.48–2.16) | 0.92 (0.70–1.21) |
ND not determined