Table 3. The baseline demographic and clinical characteristics of the 71 CAD patients in the Gensini score quartiles.
| Q1: ≤ 35.0 | Q2: 35.0–48.5 | Q3: 48.6–71.0 | Q4: > 71.0 | P value | |
|---|---|---|---|---|---|
| (n = 20) | (n = 16) | (n = 17) | (n = 18) | ||
| Age (years) | 69.1 ± 7.4 | 65.5 ± 10.3 | 69.8 ± 9.5 | 71.5 ± 11.2 | 0.340 |
| Gender (male, %) | 19 (95.0) | 12 (75.0) | 14 (72.4) | 12 (66.7) | 0.160 |
| Systolic blood pressure (mmHg) | 129 ± 20 | 136 ± 19 | 143 ± 19 | 134 ± 19 | 0.140 |
| Heart rate (beats/min) | 70 ± 14 | 68 ± 7 | 60 ± 8 | 62 ± 9 | 0.190 |
| Body mass index (kg/m2) | 24.8 ± 3.5 | 27.1 ± 4.8 | 23.6 ± 2.5 | 22.9 ± 4.0 | 0.525 |
| TRACP-5b (mU/dL) | 315.5 (270.0, 407.3) | 349.0 (247.8, 461.8) | 362.0 (285.0, 601.5) | 422.5 (341.3, 601.9) | 0.038 |
| Osteoprotegerin (pmol/L) | 83.1 (57.0, 120.8) | 112.0 (81.0, 148.0) | 82.5 (72.8, 98.2) | 98.3 (63.6, 111.0) | 0.403 |
| High-sensitivity CRP (mg/L) | 0.57 (0.21, 0.97) | 0.63 (0.34, 1.48) | 0.76 (0.28, 1.81) | 1.62 (0.47, 7.61) | 0.163 |
| LDL cholesterol (mg/dL) | 111 ± 29 | 124 ± 42 | 108 ± 26 | 112 ± 34 | 0.520 |
| HDL cholesterol (mg/dL) | 53 ± 14 | 53 ± 9 | 51 ± 10 | 51 ± 14 | 0.869 |
| Calcium (mg/dL) | 9.0 ± 0.3 | 9.1 ± 0.4 | 8.8 ± 1.6 | 8.8 ± 2.3 | 0.923 |
| eGFR (mL/min/1.73 m2) | 63.5 ± 10.6 | 65.9 ± 12.6 | 63.7 ± 18.8 | 53.1 ± 18.5 | 0.073 |
| HbA1c (%) | 6.4 ± 1.2 | 6.1 ± 0.7 | 6.0 ± 0.5 | 5.9 ± 0.5 | 0.043 |
| Number of diseased vessels | < 0.001 | ||||
| 1 | 6 | 5 | 1 | 0 | |
| 2 | 12 | 8 | 7 | 3 | |
| 3 | 2 | 3 | 9 | 15 | |
| LVEF (%) | 58.9 ± 12.7 | 57.7 ± 13.9 | 53.6 ± 12.4 | 50.5 ± 15.2 | 0.041 |
| Hypertension (%) | 18 (90.0) | 15 (93.8) | 17 (100) | 18 (100) | 0.340 |
| Diabetes (%) | 12 (60.0) | 8 (50.0) | 6 (35.3) | 6 (33.3) | 0.306 |
| Active smoker (%) | 17 (85.0) | 12 (75.0) | 12 (70.6) | 16 (88.9) | 0.491 |
The data are expressed as the mean ± SD or median (interquartile range). TRACP, tartrate-resistant acid phosphatase; differences in Gensini scores among the quartiles (Q1, Q2, Q3 and Q4); CRP, C-reactive protein; LDL, low-density lipoprotein; HDL, high-density lipoproten; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction