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Anti‐dengue activities of 7‐deazapurine nucleosides
| Compound | EC50 [μM] (assay) | CC50 [μM] | Ref. |
|---|---|---|---|
| 35a | 0.877 (replicon) | nda | 128 |
| 42 | 0.238 (replicon) | nd | 93 |
| 43b | 0.85 (Vero cells) | 1.14 | 95 |
| 72a | 0.64; 0.7 (CFI) | nd; >100 | 126, 130 |
| 72b | 0.42 (CFI) | 44 | 130 |
| 72c | 3.1 (CFI) | >100 | 130 |
| 72d | 2.0 (CFI) | 62 | 130 |
| 73 | 0.54‐0.71 (CFI) | nd | 132 |
| 74 | 0.976 (replicon) | nd | 93 |
nd, not determined
