Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 May 5;98(4):821–834. doi: 10.1099/jgv.0.000728

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors

This is an open access article under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig. 3. — Drug susceptibility of drug-resistant viruses compared to wild-type HIV-1. Drug susceptibility of the drug-resistant viruses was tested in a cell-free-based HeLa TZM-bl drug susceptibility assay. The phenotypes of the viruses were confirmed in this assay and compared to wild-type virus: (a) HIV-1dm_D was 8.4-fold more resistant to LPV than HIV-1wt but was (b) equally susceptible to DRV as HIV-1wt. (c) HIV-1m184v was as expected susceptible to AZT but was (d) 120-fold more resistant to 3TC than HIV-1wt. (e) HIV-1k103n was 28-fold more resistant to NVP than HIV-1wt, and was (f) 650-fold more resistant to EFV that HIV-1wt. The dotted lines represent actual data points while the bold lines represent the non-linear regression curve fit. The error bars represent the standard deviation of the mean and a representative experiment of two independent repeats is shown.