Table 1.
Patient’s characteristics during the EUROASPIRE IV index hospital stay by impaired kidney function
| Normal kidney function n = 362 (67.8%) | Impaired kidney function n = 172 (32.2%) | p-value | |
|---|---|---|---|
| Age, years | 64.0 (58.5; 70.4) | 72.0 (65.7; 75.1) | <0.001 |
| Male sex | 301 (83.2%) | 139 (80.8%) | 0.51 |
| Length of hospital stay (days) | 3 (1; 7) | 8 (3; 11) | <0.001 |
| Details of CHD event during index hospital stay | |||
| AMI, any | 128 (35.5%) | 75 (43.6%) | 0.07 |
| NSTEMI | 53 (41.4%) | 33 (44.0%) | 0.26 |
| STEMI | 60 (46.9%) | 28 (37.3%) | |
| Unclear/missing | 15 (11.7%) | 14 (18.7%) | |
| Therapy (max.) | <0.001 | ||
| Conservative (no intervention) | 54 (14.9%) | 29 (16.9%) | |
| PCI/stent | 279 (77.1%) | 88 (51.2%) | |
| CABG | 29 (8.0%) | 55 (32.0%) | |
| CHD history | |||
| Index event as the primary diagnosis of CHD | 162 (44.8%) | 64 (37.2%) | 0.10 |
| In those with h/o CHD | |||
| Duration of CHD, yrs. | 1.4 (0.4; 9.0) | 5.9 (0.6; 16.3) | <0.01 |
| CABG (prior to index) | 35 (17.5%) | 21 (19.4%) | 0.67 |
| PCI/stent (prior to index) | 101 (50.5%) | 55 (50.9%) | 0.94 |
| MI (prior to index) | 125 (62.5%) | 65 (60.2%) | 0.69 |
| History of heart failurea | 117 (32.7%) | 82 (48.0%) | <0.001 |
| Classic cardiovascular risk factors | |||
| Diabetesb | 98 (27.2%) | 51 (30.2%) | 0.47 |
| Hypertensionb | 299 (84.2%) | 142 (86.6%) | 0.48 |
| Hyperlipidemiab | 237 (67.1%) | 112 (70.0%) | 0.52 |
| Smokingb | 76 (22.8%) | 28 (18.9%) | 0.33 |
| Obesityc | 145 (41.1%) | 75 (47.5%) | 0.18 |
| Kidney function | |||
| SCr at admissiond, mg/dl | 0.9 (0.8; 1.0) | 1.2 (0.9; 1.3) | <0.001 |
| eGFR at admission, ml/min/1.73m2 | 86.3 (74.9; 96.3) | 59.2 (51.3; 80.5) | <0.001 |
| SCr at dischargee, mg/dl | 0.9 (0.8; 1.0) | 1.2 (1.0; 1.4) | <0.001 |
| eGFR at discharge, ml/min/1.73m2 | 85.2 (74.6; 93.8) | 57.5 (49.0; 73.8) | <0.001 |
Data are n (%), median (inter quartile range), analyses restricted to patients without missing values in respective variables
Abbreviations: CHD coronary heart disease, CABG coronary artery bypass grafting, PCI percutaneous coronary intervention, MI myocardial infarction, AMI acute myocardial infarction, STEMI ST-elevation myocardial infarction, NSTEMI non-ST-elevation myocardial infarction, SCr serum creatinine, eGFR estimated glomerular filtration rate
aKnown at hospital admission or echocardiographic findings of cardiac dysfunction
bKnown at hospital admission or stated in discharge letter
cBody mass index ≥30 kg/m2 at hospital admission or stated in discharge letter
dFirst measurement in patient record
eLast measurement in patient record