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. 2017 Oct 25;48:67. doi: 10.1186/s13567-017-0471-0

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Virulence of two H5N8 wild-type and their corresponding rescued recombinant viruses in mice. Six-week-old female BALB/c mice were intranasally inoculated with 10^3.0 EID₅₀ or 10^6.0 EID₅₀ of each indicated virus or 50 μL of PBS as controls. A Average body weight of surviving mice in each group (n = 5/group) up to 14 dpi are represented as percentages of the original weight on day 0. The error bars represent standard deviations (SD). B Survival rate of mice infected with indicated viruses.