TABLE 1.
Description of linear regression models, their outcomes, and covariates1
Outcome | Exposure | Covariates |
TL in mothers | Prenatal n–3 PUFA | Maternal age, maternal BMI, smoking, alcohol consumption, family SES at 9 mo of age |
Prenatal n–6 PUFA | ||
Prenatal n–6:n–3 PUFA ratio2 | ||
Prenatal mercury | ||
Log(TL in cord blood) | Prenatal n–3 PUFA | Maternal age, maternal BMI, smoking, alcohol consumption, family SES at 9 mo of age, child sex, birth weight, gestational age |
Prenatal n–6 PUFA | ||
Prenatal n–6:n–3 PUFA ratio2 | ||
Prenatal mercury | ||
TL at 5 y of age | Prenatal n–3 PUFA | Maternal age, maternal BMI, smoking, alcohol consumption, family SES at 5 y of age |
Prenatal n–6 PUFA | ||
Prenatal n–6:n–3 PUFA ratio2 | ||
Prenatal mercury | ||
TL at 5 y of age | Postnatal EPA+DHA | Child sex, child BMI, home environment, family SES at 5 y of age |
Postnatal AA | ||
Postnatal AA:DHA ratio3 | ||
Postnatal mercury | ||
Log(TL attrition rate) | Postnatal EPA + DHA | Child sex, child BMI, home environment, family SES at 5 y of age |
Postnatal AA | ||
Postnatal AA:DHA ratio3 | ||
Postnatal mercury |
AA, arachidonic acid; SES, socioeconomic status; TL, telomere length.
Ratio replaced n–3 PUFAs and n–6 PUFAs in the secondary prenatal model.
Ratio replaced EPA + DHA and AA in the secondary postnatal model.