NAcore mGluR2/3 antagonism prevented oxytocin from reducing meth
cue-induced reinstatement. A) Active lever presses throughout the
self-administration period for males and females. B) Inactive lever presses
throughout the self-administration period for males and females. C) Drug intake
in mg/kg in males and females. D) Lever presses during extinction for males and
females. E) Lever presses during cued reinstatement for males and females
presented separately for comparison purposes. F) Lever presses during cued
reinstatement for males and females combined.
−− indicates Veh/Sal, +− indicates LY/Sal,
−+ indicates Veh/Oxy, ++ indicates LY/Oxy
# significantly different from day 1, p<0.05
* significant difference between males and females, p<0.05
+ significantly different from Veh/Oxy group, p<0.05