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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Environ Res. 2017 Apr 3;156:253–264. doi: 10.1016/j.envres.2017.03.031

Figure 4.

Figure 4

Figure 4A. Lagged WQS: Time-varying joint/mixture and individual effects of Mn, Pb and Zn on behavioral outcome. On the first plot, the y-axis represents the time-varying coefficient of the mixture effect. Yellow: 95% CIs unadjusted for multiple testing, adjusted for intra-subject correlations; bars: Holm-Bonferroni adjustment for multiple testing

Figure 4B. Tree-based DLMs - Time-varying individual and joint/mixture effects of Mn, Pb and Zn on neuro-behavioral outcome. In the upper panel, time windows with significant mixture/joint effects are denoted by red circles. Orange circles denote marginally significant (at the 10% significance level) mixture effects. The lower panel plot shows the contributions of each chemical over time.