Table 3.
Association of baseline accelerometry measures with MMD and PMMD when fitting different levels of activity jointly.
| Event | Model 1 | Model 2 | Model 3 | Model 4 | |
|---|---|---|---|---|---|
| MMD | Minutes/day 100–499 cpm | 0.86 (0.77, 0.95) | 0.85 (0.77, 0.94) | 0.88 (0.8, 0.97) | 0.89 (0.8, 0.98) |
| Minutes/day 500–1039 cpm | 0.91 (0.69, 1.19) | 0.94 (0.72, 1.23) | 0.97 (0.75, 1.25) | 1 (0.77, 1.31) | |
| Minutes/day > 1039 cpm | 0.43 (0.28, 0.65) | 0.45 (0.3, 0.68) | 0.77 (0.51, 1.15) | 0.77 (0.51, 1.17) | |
| Minutes/day 100–499 cpm | 0.88 (0.8, 0.98) | 0.88 (0.79, 0.97) | 0.89 (0.8, 0.98) | 0.89 (0.81, 0.99) | |
| Minutes/day 500–1039 cpm | 0.92 (0.71, 1.21) | 0.95 (0.73, 1.24) | 0.99 (0.77, 1.28) | 1.03 (0.79, 1.34) | |
| Minutes/day > 1039 cpm | 0.31 (0.2, 0.48) | 0.33 (0.21, 0.51) | 0.61 (0.39, 0.96) | 0.65 (0.41, 1.04) | |
| Interaction between Minutes/day 500–1039 cpm and > 1039 cpm | 1.54 (1.3, 1.81) | 1.51 (1.28, 1.78) | 1.24 (1.03, 1.48) | 1.18 (0.97, 1.44) | |
| PMMD | Minutes/day 100–499 cpm | 0.86 (0.75, 0.99) | 0.85 (0.74, 0.98) | 0.89 (0.78, 1.01) | 0.9 (0.78, 1.03) |
| Minutes/day ≥ 500 cpm | 0.79 (0.54, 1.17) | 0.85 (0.57, 1.24) | 0.9 (0.63, 1.3) | 0.96 (0.66, 1.39) | |
| Minutes/day > 1039 cpm | 0.36 (0.2, 0.67) | 0.37 (0.2, 0.69) | 0.74 (0.41, 1.34) | 0.78 (0.43, 1.43) | |
| Minutes/day 100–499 cpm | 0.89 (0.77, 1.02) | 0.88 (0.76, 1) | 0.9 (0.78, 1.02) | 0.9 (0.79, 1.03) | |
| Minutes/day 500–1039 cpm | 0.82 (0.56, 1.21) | 0.87 (0.59, 1.28) | 0.92 (0.64, 1.32) | 0.97 (0.67, 1.41) | |
| Minutes/day > 1039 cpm | 0.28 (0.15, 0.54) | 0.29 (0.15, 0.55) | 0.66 (0.34, 1.27) | 0.73 (0.37, 1.43) | |
| Interaction between Minutes/day 500–1039 cpm and > 1039 cpm | 1.58 (1.23, 2.03) | 1.55 (1.2, 2) | 1.15 (0.85, 1.57) | 1.09 (0.79, 1.51) |
Data expressed as HR (95% CI); all models adjusted for accelerometer wear time
Model 1 stratifies for site and sex, and adjusts for randomization ; Model 2 adjusted for model 1, race, age, and education
Model 3 adjusted for model 2, baseline Short Physical Performance Battery Score, baseline 400 m walking speed, and co-morbidity burden
Model 4 adjusted for model 3, use of anti-hypertensive and lipid-lowering drugs, sleep quality, and depression
Bold if p-value < 0.05