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. Author manuscript; available in PMC: 2017 Nov 24.
Published in final edited form as: Nature. 2017 May 24;546(7656):113–117. doi: 10.1038/nature22397

Figure 1. Cryo-EM structures of cognate or near-cognate ternary complex on the 70S ribosome.

Figure 1

(a) Cognate (green) and near-cognate (blue) tRNA anticodons and A-site codons used in complexes. (b) Structure I has cognate TC on the ribosome with an open 30S subunit; the anticodon and codon are not paired. (c) Structure II has cognate TC on the ribosome with an open 30S subunit; the anticodon base-pairs with the codon. (d) Structure III has cognate TC on the ribosome with a closed 30S subunit; EF-Tu docks at the sarcin-ricin loop (SRL). (e–g) Structures I-nc, II-nc, and III-nc with near-cognate TC globally resemble the cognate Structures.