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. Author manuscript; available in PMC: 2017 Nov 24.
Published in final edited form as: Nature. 2017 May 24;546(7656):113–117. doi: 10.1038/nature22397

Figure 3. Decoding-center rearrangements in Structures I to III.

Figure 3

(a) Disengaged DC of Structure I. (b) In Structure II, G530 adopts an intermediate position at the minor groove of the codon-anticodon helix. A1492 has partial occupancies inside and outside of helix 44 (gray). (c) In Structure III, G530 moves farther into the minor groove and hydrogen-bonds to A1492. (d–e) Cryo-EM density (gray) showing G530 (yellow) in Structures II (d) and III (e).