Table IV.
Bayesian analysis* of ICD efficacy by NYHA class
| NYHA class | Group | HR | Lower PCI | Upper PCI |
|---|---|---|---|---|
| II | DEFINITE | 0.55 | 0.36 | 0.81 |
| MADIT I | 0.50 | 0.28 | 0.71 | |
| MADIT II | 0.52 | 0.36 | 0.69 | |
| SCD-HeFT | 0.61 | 0.49 | 0.79 | |
| Overall | 0.55 | 0.35 | 0.85 | |
| III | DEFINITE | 0.77 | 0.50 | 1.20 |
| MADIT I | 0.68 | 0.37 | 1.00 | |
| MADIT II | 0.71 | 0.50 | 0.99 | |
| SCD-HeFT | 0.84 | 0.66 | 1.08 | |
| Overall | 0.76 | 0.48 | 1.24 |
*
Adjustment for age, sex, race, ejection fraction, QRS duration >120 milliseconds, ischemic heart disease, antiarrhythmic drug use, β-blockers, ACE inhibitors, smoking, and diabetes and an interaction term for NYHA class and ICD use. Posterior probability of no interaction = .036.