Figure 6.

Relationship of normal mouse whole brain uptake and logPC18 (logarithm of the octanol-water partition coefficient estimated by relative HPLC retention on a lipophilic C18 column) of different 11C-labeled-BTA compounds at 2 min following intravenous tail-vein injection. Note that the brain uptake SUV of most BTAs exceeded 1.0. (adapted from (56)).