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. Author manuscript; available in PMC: 2018 Sep 21.
Published in final edited form as: Mol Cell. 2017 Aug 31;67(6):1013–1025.e9. doi: 10.1016/j.molcel.2017.07.028

Figure 6.

Figure 6

MYC-mediated effects on cell fate during the DNA DSB response. (A–C) Cell cycle distributions of MYC-GFP and GFP cells that were (A) not treated with NCS, (B) treated with NCS for 24 h, or (C) treated with NCS for 48 h. Data are represented as mean ± SEM (n = 3). (D) Annexin V (AV) and propidium iodide (PI) staining showing the percentage of cells in early apoptosis (high AV, low PI) and late apoptosis (high AV, high PI) in RPE1 MYC-GFP and RPE1 GFP cells after the indicated treatments. Data are represented as mean ± SEM (n = 4). Asterisks (*) denote statistically significant differences between MYC-GFP and GFP cells or between RPE1 MYC-GFP and RPE1 GFP cells (p < 0.05, two-sample T test).