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. 2017 May 1;26(5):805–820. doi: 10.3727/096368916X694274

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Figure 7. — ZD significantly increased and stable knockdown of miR-210 impaired the therapeutic efficacy of transplanted hADMSCs in a murine ALF model, respectively. (A) Mice survival numbers were recorded for 7 days with indicated treatments. (B, C) Representative hepatic H&E images (200x) and corresponding liver necrosis quantification of mice at day 1 and day 7 that received indicated treatments. White dashed line defined areas that are typical necrotic and inflammatory sites in the liver. (D) Expanded cell number in the host mice liver after stem cell transplantation. *p < 0.05, **p < 0.01, ***p < 0.001 mean significant changes between indicated groups, respectively. Ctrl, control; GL, Gal/LPS cotreatment; hADMSCs, human adipose-derived mesenchymal stem cells; KD, stable knockdown of miR-210; Gal, galactosamine; LPS, lipopolysaccharide; miR-210, microRNA-210; v-, vehicle-.