Figure 4.

Effect of peptide preconditioning on the adhesion of CD34- and CD34⁺ cells onto vitronectin–collagen matrix. (A) All patients (diabetic plus nondiabetic). (B) Diabetic (gray bars) versus nondiabetic patients (white bars). Results are expressed as number of adherent cells per 2 × 10³ seeded cells. ∗∗∗p < 0.001 (Kruskal–Wallis test). Effect of preconditioning with TSP-1 peptides on the adhesion of CD34⁺ (nonhashed bars) and CD34- cells (hashed bars) in diabetic (gray bars) versus nondiabetic patients (white bars) on HUVEC monolayers prestimulated by TNF-α (C) or IL-1b (D). Results are expressed as number of adherent cells per 10³ seeded cells (p > 0.05, Kruskal–Wallis test). HUVEC, human umbilical vein endothelial cell; TNF, tumor necrosis factor; TSP, thrombospondin; T2D, type 2 diabetes; non-T2D, nondiabetic; NS, not significant. ∗∗∗p < 0.001 (ANOVA).