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. Author manuscript; available in PMC: 2017 Oct 26.
Published in final edited form as: Vitam Horm. 2016 Mar 24;101:257–310. doi: 10.1016/bs.vh.2016.02.007

Table 3.

Potential Applications of αKlotho in Chronic Kidney Disease

Biomarker Therapeutic Agent
Diagnostic Early detection of CKD Prevention

  • CKD progression

  • CV comorbidity and complications
Prognostic Prediction of progression to ESRD Treatment

  • Anti-Pi toxicity

  • Attenuation of CV

CKD, chronic kidney disease; CV, cardiovascular event; ESRD, end-stage renal disease.