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. 2017 Oct 26;12(10):e0186854. doi: 10.1371/journal.pone.0186854

Fig 5. Boost by adjuvanted RSV F DS-Cav1 can focus the RSV immune response to antigenic site Ø and II in elderly mice.

Fig 5

Pre-immunized elderly mice (~85 weeks wait) were administered (A) DS-Cav1 formulated with SAS + Carbopol or (B) DS-Cav1 formulated with Alum and recognition of DS-Cav1, DS-Cav1 site Ø KO, DS-Cav1 site II KO, Post F and Post F site II KO probes by sera for all immunized mice assessed. Scatter plots show the geometric mean. p values were determined by two-tailed Wilcoxon matched-pairs signed rank test, p = >0.05 (ns); p < 0.05 (*). Associated raw data is reported in S5 Table.