Skip to main content
. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Converg Sci Phys Oncol. 2017 May 17;3(2):023001. doi: 10.1088/2057-1739/aa6c05

Figure 1.

Figure 1

Platelets can support and encourage cancer cell metastasis by (A) shielding cancer cells from immune cells during vascular dissemination, (B) arresting cancer cells on the wall of a blood vessel, and (C) releasing growth factors that allow for extravasation of cancer cells through the endothelial cell and extracellular matrix barrier. (Key - TGFβ - transforming tumor growth factor β; MMP - matrix metalloproteases; VEGF - vascular endothelial growth factor; PDGF - platelet derived growth factor; ADP - adenosine diphosphate; ATP - adenosine triphosphate).