Table 4. Comparison of the peripapillary retinal nerve fibre layer thickness between non-arteritic anterior ischaemic optic neuropathy eyes and normal fellow eyes.
NAION eye | Fellow eye | Reduction rate (%)* | P value† | |
---|---|---|---|---|
Average RNFL thickness | 64.7 ± 12.3 | 93.0 ± 7.6 | 30.4 | <0.001 |
Quadrant RNFL thickness | ||||
Superior | 70.8 ± 22.6 | 111.9 ± 11.8 | 36.7 | <0.001 |
Nasal | 54.4 ± 10.0 | 67.3 ± 9.8 | 19.2 | <0.001 |
Inferior | 80.0 ± 23.5 | 124.2 ± 16.1 | 35.6 | <0.001 |
Temporal | 53.1 ± 12.1 | 68.9 ± 10.2 | 23.0 | <0.001 |
Clock-hour RNFL thickness | ||||
11 o’clock | 73.5 ± 25.2 | 119.0 ± 22.7 | 38.2 | <0.001 |
12 o’clock | 75.8 ± 27.4 | 114.0 ± 19.8 | 33.5 | <0.001 |
1 o’clock | 62.5 ± 17.3 | 103.0 ± 18.1 | 39.3 | <0.001 |
2 o’clock | 57.8 ± 14.8 | 78.1 ± 16.8 | 26.1 | <0.001 |
3 o’clock | 51.8 ± 9.5 | 60.3 ± 8.3 | 14.1 | 0.005 |
4 o’clock | 53.1 ± 7.8 | 62.5 ± 10.8 | 15.0 | 0.001 |
5 o’clock | 64.4 ± 16.1 | 98.2 ± 17.3 | 34.4 | <0.001 |
6 o’clock | 81.8 ± 28.9 | 136.4 ± 25.1 | 40.0 | <0.001 |
7 o’clock | 93.7 ± 29.6 | 138.2 ± 19.8 | 44.5 | <0.001 |
8 o’clock | 55.1 ± 14.3 | 69.5 ± 12.2 | 20.7 | 0.001 |
9 o’clock | 48.8 ± 10.7 | 56.0 ± 8.1 | 13.0 | 0.004 |
10 o’clock | 55.0 ± 17.7 | 81.1 ± 15.6 | 32.2 | <0.001 |
(μm, mean ± SD)
RNFL = retinal nerve fibre layer, GCIPL = ganglion cell plus inner plexiform layer
NAION = non-arteritic anterior ischaemic optic neuropathy
*Reduction rate (%) = 100 × (RNFL thickness of the fellow eye–RNFL thickness of the NAION eye)/RNFL thickness of the fellow eye
† Axial length adjusted linear mixed model.