Table 1. Patient characteristics.
| Lean controls (n = 15) | Obese—pre (n = 13) | Obese—post (n = 13 | |
|---|---|---|---|
| Girls (number, %) | 8 (53.3) | 7 (53.8) | 7 (53.8) |
| Age (years) | 11.7 ± 2.9 | 10.7 ± 3.9 | 12.0 ± 3.9 |
| BMI | 18.5 ± 2.6 *# | 27.9 ± 5.2 * | 28.2 ± 5.5 # |
| BMI-SD | 0.5 ± 0.9 *# | 3.3 ± 0.7 * | 3.1 ± 0.7 # |
| Waist (cm) | 64.5 ± 7.5 *# | 94.4 ± 16.8 * | 98.4 ± 17.0 # |
| Systolic blood pressure (SBP) | 102.2 ± 12.7 *# | 113.2 ± 12.2 * | 114.8 ± 11.7 # |
| SBP percentile | 39.9 ± 23.6 *# | 65.7 ± 25.1 * | 65.5 ± 28.4 # |
| Diastolic blood pressure (DBP) | 57.7 ± 8.2 *# | 67.2 ± 9.5 * | 69.4 ± 10.5 # |
| DBP percentile | 35.9 ± 19.9 *# | 62.6 ± 23.9 * | 65.4 ± 27.1 # |
| QUICKI | 0.4 ± 0.0 *# | 0.3 ± 0.0 * | 0.3 ± 0.0 # |
| Alanine aminotransferase (U/l) | 18.0 (14.5–21.8) *# | 29.5 (22.2–53.9) * | 30.3 (22.9–41.2) # |
| Triacylglycerol (mmol/l) | 0.6 ± 0.3 * | 1.0 ± 0.4 * | 1.0 ± 0.7 |
| Total cholesterol (mmol/l) | 4.0 ± 0.8 | 4.0 ± 0.8 | 3.9 ± 0.9 |
| HDL-cholesterol (mmol/l) | 1.7 ± 0.9 | 1.2 ± 0.3 | 1.3 ± 0.2 |
| LDL-cholesterol (mmol/l) | 2.2 ± 0.7 | 2.3 ± 0.7 | 2.2 ± 0.8 |
| Adiponectin (ug/ml) | 18.9 (15.6–26.5) | 12.9 (9.5–21.3) | 13.6 (10.4–19.8) |
| Chemerin (ug/ml) | 1.2 (1.0–1.7) *# | 1.9 (1.8–2.7) * | 2.3 (1.8–2.5) # |
| Leptin (ng/ml) | 125 (16–195) *# | 399 (219–692) * | 411 (308–600) # |
Clinical characteristics and laboratory parameters for lean controls versus obese children pre-lifestyle intervention (pre) and post-lifestyle intervention (post). Normally distributed data are shown as mean ± SD, non-parametric data as median (interquartile range).
* p<0.05 for lean controls compared to obese-pre.
# p<0.05 for lean controls versus obese-post.