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. 2017 Oct 26;12(10):e0187168. doi: 10.1371/journal.pone.0187168

Fig 2. Sterol quantifications in the brain of Cyp46a1-/- mice and wild type controls.

Fig 2

Data for cholesterol, lathosterol, desmosterol, 24-hydroxycholesterol, and 27-hydroxycholesterol were taken from [49]. The data represent the mean ± SD of three measurements in individual (n = 3) 3–5 month old mice. Statistical significance was assessed two-way ANOVA followed by pairwise comparisons made using the Bonferroni correction. Significant comparisons of free sterols are denoted by the following color code: pink asterisks, significant changes between Cyp46a1-/- females versus wild type females; blue asterisks, significant changes between Cyp46a1-/- males versus wild type males; gray asterisks, significant changes between female and male mice of the same strain; and black asterisks, significant changes between the genotypes when data were collapsed across genders. *, P≤0.05; **, P≤0.01; ***, P≤0.001; and ND, not detectable (the limit of detection was 1 pmol/mg protein).