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. 2017 Oct 26;12(10):e0187160. doi: 10.1371/journal.pone.0187160

Table 1. Comparison of subject characteristics according to the myopic degree and optic disc rotation direction.

Variables Overall
(n = 150)
Degree of myopia Optic disc rotation direction
Non-high myopia
(n = 98)
High myopia
(n = 52)
p value* Superior
(n = 79)
Inferior
(n = 71)
p value
Age (yrs) 23.39 ± 3.85 23.80 ± 3.66 22.62 ± 4.11 0.074 23.44 ± 3.93 23.32 ± 3.78 0.851
Sex (male/female) 99 / 51 64 / 34 35 /17 0.476 55 / 24 44 / 27 0.389
SE refractive error (D) -5.34 ± 2.72 -3.72 ± 1.40 -8.38 ± 1.83 < 0.001 -4.96 ± 2.49 -5.76 ± 2.91 0.077
IOP (mmHg) 14.87 ± 2.44 14.70 ± 2.35 15.17 ± 2.61 0.265 14.38 ± 2.58 15.41 ± 2.17 0.009
Axial length (mm) 26.05 ± 1.25 25.46 ± 0.98 27.14 ± 0.96 < 0.001 25.96 ± 1.23 26.14 ± 1.29 0.379
Central corneal thickness (μm) 558.21 ± 35.37 558.34 ± 37.64 557.96 ± 31.01 0.951 555.72 ± 30.52 260.97 ± 40.14 0.373
Disc area (mm2) 1.86 ± 0.40 1.88 ± 0.45 1.80 ± 0.25 0.071 1.85 ± 0.33 1.87 ± 0.46 0.818
Vertical CDR 0.48 ± 0.15 0.49 ± 0.16 0.45 ± 0.15 0.081 0.45 ± 0.14 0.61 ± 0.17 0.061
Ovality index 1.31 ± 0.13 1.31 ± 0.12 1.33 ± 0.14 0.340 1.31 ± 0.13 1.32 ± 0.12 0.609
Optic disc rotation degree (°) 1.57 ± 15.60 -0.31 ± 15.07 5.12 ± 16.10 0.042§ -11.95 ± 4.66 16.62 ± 7.60 < 0.001§
Area of β-PPA (mm2) 0.96 ± 0.42 0.90 ± 0.41 1.08 ± 0.41 0.010 0.86 ± 0.37 1.07 ± 0.45 0.002
Average pRNFL thickness (μm) 98.71 ± 7.97 100.95 ± 6.79 94.48 ± 8.37 < 0.001 99.27 ± 7.09 98.08 ± 8.86 0.367
Whole en face vessel density of RPC segment (%) 55.16 ± 2.40 55.74 ± 2.24 54.06 ± 2.35 < 0.001 55.46 ± 2.08 54.82 ± 2.69 0.100
Inside disc vessel density (%) 47.66 ± 8.13 46.85 ± 8.51 49.17 ± 7.21 0.097 48.79 ± 7.99 46.39 ± 8.15 0.073
Superficial peripapillary microvascular density (%) 62.14 ± 5.47 63.03 ± 2.56 60.49 ± 3.46 < 0.001 62.38 ± 2.90 61.88 ± 3.39 0.336
Deep peripapillary microvascular density (%) 73.76 ± 4.02 73.60 ± 4.22 74.05± 3.64 0.525 75.05± 3.71 72.32± 3.89 < 0.001

SE = spherical equivalent; D = diopters; IOP = intraocular pressure; CDR = cup-to-disc ratio; PPA = peripapillary atrophy; pRNFL = peripapillary retinal nerve fiber layer; RPC = radial peripapillary capillary.

* Comparisons between the non-high myopia and high myopia groups using an independent-t test or chi-square test as appropriate.

Comparisons between the superior rotation and inferior rotation groups using an independent-t test or chi-square test as appropriate.

All IOP measurements were made between 4:00 and 6:00 pm.

§ The comparison was done with the unsigned value.