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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Jul 20;37(11):2102–2113. doi: 10.1161/ATVBAHA.117.309401

Figure 1.

Figure 1

Experimental time course and groups. (A) Mice are enrolled at 6 weeks of age and receive daily tamoxifen injections for 5 days. Two weeks after the last injection, mice are implanted with osmotic minipumps that release angiotensin II (Ang II) for 28 days. During the Ang II infusion, antibodies are injected every three days. Mice are euthanized on day 48. (B) Genotypes, treatments, and number of mice enrolled in each of the 3 experimental groups. The numbers of male and female mice reflect those that completed the study.