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. 2017 Sep 28;93(4):173–180. doi: 10.4174/astr.2017.93.4.173

Table 1C. Comparison of mutations in intragenerational patient-derived tumor xenograft (PDTX) models.

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Colon cancer mutation profiling was preserved across the PDTX model generations EGFR(18,19,20,21), KRAS(2), BRAF(15), PIK3CA(9,20), NRAS, APC(16) and TP53(5,6,7,8).