Fig. 5. Comparison of neutrophils' inflammatory response with or without lipopolysaccharide (LPS) insult between hypoxia-normoxia and hypoxia-hyperoxia groups. (A, B) There were no differences in production of hydrogen peroxide (H₂O₂) between hypoxia-normoxia and hypoxia-hyperoxia groups with or without LPS insult. (A, B) Delay of apoptosis was prominent in hypoxia-normoxia group without LPS insult compared to hypoxia-hyperoxia group with LPS insult. (A, B) Toll-like receptor 4 (TLR₄) receptor production was decreased in hypoxia-hyperoxia group with or without LPS insult compared to hypoxia-normoxia group with or without LPS insult. Mean ± standard deviation (n = 18). ^*P < 0.05, paired t-test.