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. 2017 Oct 26;7:14089. doi: 10.1038/s41598-017-14372-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of dCACHE LBD of TlpC with structures of other dCACHE domains. (a,b) Structural superposition of TlpC LBD (C_α trace, in red) with dCACHE domains of (a) Tlp1 (C_α, in green, PDB entry 4wy9²⁴) and (b) HK1s-Z8 (C_α, in blue, PDB entry 3lie⁴³). (c) LBDs of TlpC, Tlp1 (PDB entry 4wy9²⁴), HK1s-Z8 (PDB entry 3lie⁴³), Tlp3 (PDB entry 4xmq²³), HK1s-Z3 (PDB entry 3lib⁴³), Mlp37 (PDB entry 5ave⁵¹), DctB (PDB entry 3by9⁵²) and LuxQ (PDB entry 1zhh⁵³).