Table 3.
Refinement statistics.
| Data set | TlpC native | Co-crystal with 10 mM lactate |
|---|---|---|
| Resolution range (Å) | 30.6–2.2 | 30.0–2.5 |
| No. reflections | 59,028 | 40,012 |
| Rwork/Rfree a | 0.182/0.218 | 0.192/0.251 |
| No. atoms | ||
| Protein | 6310 | 6212 |
| Water | 452 | 66 |
| Lactate | 18 | 18 |
| B-factors | ||
| Average B (protein atoms) (Å2) | 46 | 42 |
| Average B (water molecules) (Å2) | 52 | 37 |
| Average B (lactate) (Å2) | 41 | 41 |
| R.m.s. deviations from ideality | ||
| Bond lengths (Å) | 0.017 | 0.008 |
| Bond angles (°) | 1.4 | 1.1 |
aThe Rfree was calculated on 5% of the data omitted at random.