Table 4.
Effects of drug resistance mutations and viral subtypes on CD4 cells counts and viral load.
| Parameters | Status | Subtypes | DRMs | ||
|---|---|---|---|---|---|
| 02_AG | Non-02_AG | NRTIs | NNRTIs | ||
| Mean CD4 ± SD (Cells/µl) | (n = 95) | (n = 46) | (n = 14) | (n = 18) | |
| ART (n = 18) | 350.4 ± 276.7 | 321.4 ± 141.2 | 291.4 ± 108 | 336.2 ± 343 | |
| Naïve (n = 74) | 353.9 ± 256.3 | 313.1 ± 191.8 | 148.3 ± 79.5 | 260.0 ± 246.8 | |
| P -value | 0.959 | 0.886 | 0.042 | 0.605 | |
| Mean VL ± SD (log copies/ml) | ART (n = 18) | 3.31 ± 1.34 | 2.8 ± 1.56 | 2.7 ± 1.4 | 3.13 ± 1.5 |
| Naïve (n = 74) | 4.48 ± 1.59 | 4.6 ± 1.2 | 3.77 ± 1.52 | 4.57 ± 1.64 | |
| P -value | 0.0049 | 0.0002 | 0.256 | 0.07 | |
VL: Viral Load; DRMs: Drug Resistance Mutation; SD: standard deviation; 02_AG: HIV-1 CRF02_AG; n: sample size NRTI: Nucleoside/Nucleotide Reverse Transcriptase Inhibitors; NNRTI: Non- Nucleoside/Nucleotide Reverse Transcriptase Inhibitor; ART: antiretroviral therapy.