Table 2.
Summary of the RECIST 1.1 and Choi criteria for treatment response evaluation
| Response | Definition |
|---|---|
| CT response evaluation criteria according to RECIST 1.1 | |
| CR | Disappearance of all lesions |
| Reduction to <10 mm in short axis of any pathological lymph nodes (whether target or non-target) | |
| No new lesions | |
| PR | At least a 30% decrease in SLD of target lesions, taking as reference the baseline SLD |
| No new lesions | |
| SD | Does not meet the criteria for CR, PR, or PD |
| PD | At least a 20% increase in SLD of target lesions, taking as reference the smallest
sum
on
study
and at least 5 mm absolute increase in SLD |
| New lesions | |
| Modified CT response evaluation criteria according to Choi | |
| CR | Disappearance of all lesions |
| No new lesions | |
| PR | A decrease in sizea of ≥10% or a decrease in tumor density (HU) ≥15% on CT |
| No new lesions | |
| No obvious progression of nonmeasurable disease | |
| SD | Does not meet the criteria for CR, PR, or PD |
| No symptomatic deterioration attributed to tumor progression | |
| PD | An increase in tumor size of ≥10% and does not meet criteria of PR by tumor density (HU) on CT |
| New lesions | |
| New intratumoral nodules or increase in the size of the existing intratumoral nodules | |
CR complete response, PR partial response, HU Hounsfield unit, CT computed tomography, SD stable disease, PD progression of disease, RECIST Response Evaluation Criteria in Solid Tumors
a SLD The sum of longest diameters of target lesions as defined in RECIST