Table 2.

Associations between BMI at ages 15 to 60–64 and hip modes (HM) 1 to 6 at 60–64 years in the MRC NSHD, by sex.

BMI per 1 kg/m2 at age:	Men	P valuea	Women	P valuea
	β (95%CI)		β (95%CI)
HM 1
15	0.014 (− 0.019, 0.048)	0.4	0.027 (0.001, 0.054)	0.04
20	0.010 (− 0.024, 0.045)	0.6	0.013 (− 0.012, 0.038)	0.3
26	0.016 (− 0.012, 0.044)	0.3	0.018 (− 0.005, 0.041)	0.1
36	− 0.005 (− 0.031, 0.020)	0.7	0.005 (− 0.015, 0.025)c	0.6
43	− 0.002 (− 0.025, 0.022)	0.9	0.002 (− 0.014, 0.018)c	0.8
53	0.003 (− 0.017, 0.023)	0.8	0.001 (− 0.012, 0.015)c	0.8
60–64	− 0.009 (− 0.027, 0.009)	0.3	0.001 (− 0.011, 0.013)	0.9
HM 2
15	0.065 (0.031, 0.098)	< 0.001	0.075 (0.049, 0.101)	< 0.001
20	0.06 (0.025, 0.095)c	0.001	0.071 (0.046, 0.096)	< 0.001
26	0.071 (0.042, 0.099)	< 0.001	0.068 (0.045, 0.090)	< 0.001
36	0.065 (0.039, 0.091)	< 0.001	0.052 (0.033, 0.072)	< 0.001
43	0.054 (0.030, 0.077)	< 0.001	0.045 (0.030, 0.061)	< 0.001
53	0.050 (0.030, 0.07)	< 0.001	0.039 (0.027, 0.052)	< 0.001
60–64	0.048 (0.030, 0.066)	< 0.001	0.040 (0.028, 0.052)	< 0.001
HM 3
15	− 0.001 (− 0.035, 0.033)c	0.9	− 0.022 (− 0.048, 0.003)	0.09
20b	− 0.032 (− 0.065, 0.001)	0.06	0.012 (− 0.013, 0.037)	0.3
26	− 0.0003 (− 0.028, 0.028)	> 0.9	0.015 (− 0.007, 0.038)	0.2
36b	− 0.016 (− 0.042, 0.009)d	0.2	0.018 (− 0.001, 0.037)	0.07
43b	− 0.017 (− 0.040, 0.007)c	0.2	0.016 (0.001, 0.032)	0.04
53b	− 0.011 (− 0.032, 0.009)	0.3	0.014 (0.001, 0.026)	0.03
60–64b	− 0.010 (− 0.028, 0.008)	0.3	0.015 (0.003, 0.027)	0.01
HM 4
15b	− 0.094 (− 0.129, − 0.059)	< 0.001	− 0.006 (− 0.032, 0.019)	0.6
20b	− 0.052 (− 0.087, − 0.017)	0.004	− 0.0004 (− 0.024, 0.024)	> 0.9
26	− 0.036 (− 0.066, − 0.006)	0.02	− 0.008 (− 0.029, 0.014)	0.5
36b	− 0.043 (− 0.071, − 0.016)	0.002	0.005 (− 0.013, 0.023)	0.6
43b	− 0.039 (− 0.064, − 0.014)	0.002	0.002 (− 0.013, 0.017)	0.8
53b	− 0.035 (− 0.056, − 0.013)	0.001	0.005(− 0.007, 0.017)	0.4
60–64b	− 0.026 (− 0.045, − 0.007)	0.007	0.003 (− 0.009, 0.015)	0.6
HM 5
15	0.031 (− 0.004, 0.067)	0.08	0.050 (0.024, 0.076)	< 0.001
20	0.02 (− 0.016, 0.056)	0.3	0.042 (0.017, 0.067)	0.001
26	0.014 (− 0.016, 0.043)	0.4	0.036 (0.013, 0.059)	0.002
36	0.019 (− 0.007, 0.046)	0.2	0.021 (0.001, 0.04)c	0.04
43	0.008 (− 0.017, 0.032)	0.5	0.011 (− 0.005, 0.028)	0.2
53	0.009 (− 0.011, 0.03)	0.4	0.007 (− 0.006, 0.021)	0.3
60–64	− 0.0003 (− 0.019, 0.018)c	> 0.9	0.012 (− 0.001, 0.024)	0.06
HM 6
15	− 0.007 (− 0.039, 0.025)	0.7	− 0.015 (− 0.042, 0.013)	0.3
20	0.021 (− 0.012, 0.053)	0.2	− 0.001 (− 0.028, 0.025)	0.9
26	0.0002 (− 0.027, 0.027)	> 0.9	− 0.007 (− 0.031, 0.017)	0.6
36	0.020 (− 0.005, 0.044)	0.1	0.0003 (− 0.020, 0.021)	> 0.9
43	0.016 (− 0.007, 0.038)	0.2	− 0.003 (− 0.019, 0.014)	0.8
53	0.015 (− 0.004, 0.034)	0.1	0.005 (− 0.009, 0.019)	0.5
60–64	0.017 (− 0.001, 0.034)c	0.06	0.001 (− 0.012, 0.014)	0.8

Models are run on the maximum available N at each age (See Table 1).

^aWald's p value.

^bsex-interaction p < 0.05.

^csignificant quadratic term but deviation from linearity was not confirmed when BMI was modelled as sex-specific fifths.

^dnon-linear relationship (LRT for quadratic term, p = 0.014) but weak overall LRT for BMI (p = 0.051).