Table IV.
Effects of wogonin on the TYR activity of A375 cells.
| Group (µmol/l) | OD | OD treatment group/OD control group (%) |
|---|---|---|
| Control group (−) | 0.085±0.005 | 100.00 |
| Estradiol group (10−3) | 0.106±0.004a | 124.71a |
| Wogonin group (10) | 0.054±0.004a | 63.53a |
| Wogonin group (10) + ICI182780 (1) | 0.071±0.011a,b | 83.53a,b |
| Wogonin group (10) + U0126 (10) | 0.066±0.009a,b | 77.65a,b |
Data are presented as the mean ± standard deviation (n=6).
a
P<0.01 vs. the control group
b
P<0.01 vs. the wogonin group. ICI182780, estrogen inhibitor; U0126, extracellular signal-regulated kinase inhibitor; OD, optical density; TYR, tyrosinase.