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(A) LDF measurement showed that hindlimb perfusion remained reduced in Gja5-/− mice compared to Gja5+/+ mice (P=0.000187313) at 3 days after FAO. (B) LDF imaging 7 days after FAO demonstrated that hindlimb perfusion remained reduced in Gja5-/− mice compared with Gja5+/+ mice (P<0.001). LDF, Laser Doppler Blood Flow; FAO, femoral artery occlusion; Gja5, gap junction protein α 5.
