Table II.
Correlation between 10 SNP sites and PCOS by comparison of allele frequency between patients and control groups.
| Allele frequency | |||||
|---|---|---|---|---|---|
| SNPs | Gene | Allele | PCOS group | Control group | P-value |
| rs346795081 | THADA | A/C | 0.426 | 0.358 | <0.05 |
| rs346796267 | THADA | C/G | 0.343 | 0.339 | >0.05 |
| rs346797283 | DENND1A | A/C | 0.324 | 0.321 | >0.05 |
| rs346803513 | DENND1A | A/T | 0.447 | 0.412 | <0.05 |
| rs346982406 | DENND1A | A/T | 0.128 | 0.125 | >0.05 |
| rs346996092 | TOX3 | C/T | 0.268 | 0.257 | >0.05 |
| rs346999236 | TOX3 | C/T | 0.321 | 0.295 | <0.05 |
| rs347021263 | YAP1 | A/T | 0.179 | 0.186 | >0.05 |
| rs347026725 | YAP1 | A/T | 0.351 | 0.350 | >0.05 |
| rs347029500 | YAP1 | C/T | 0.342 | 0.325 | <0.05 |
P<0.05, statistically significant differences. SNPs, single nucleotide polymorphisms; PCOS, presence of polycystic ovary syndrome.