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. 2017;4(4):247–253.

Table 2.

Selected series outcomes of relapsed or refractory PCNSL patients treated with SRS

Author n Single or Multi-institutional Data Collection Median Margin Dose Median Tumor Volume 1 Year PFS/OS 1 year LC
Sakamoto et al. 10 9 Single Retrospective 12 Gy 3.5 cm3 22%/58% 89%
Kenai et al. 17 22 Single Retrospective 16.5 Gy 4 cm3 Not Reported 100%
Matsumoto et al. 18 6 Single Retrospective Not Reported Not Reported Median PFS/OS: 11 months/17 months 67%
Kumar et al. 19 14 Single Retrospective 15.5 Gy 6.7 cm3 Median PFS/OS: 4 months/9.5 months 78%
Current Study 23 Multi Retrospective 15 Gy 4 cm3 55%/47% 75%

PCNSL Primary Central Nervous System Lymphoma, SRS Stereotactic radiosurgery, PFS Progression-free survival, OS Overall survival, LC Local Control