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. 2013;2(4):257–271.

Table 1.

Variation in the number of iso-centers and overall treatment times used on a series of patients with large Vestibular Schwannomas. The prescription dose varied between 14 and 10 Gy, delivered to the 40 – 60 % iso-dose using a Series-B Gamma Knife.

Prescription dose (Gy)/ Overall treatment time (min)
Iso-center number 20-30 30-40 40-50 50-60 60-70 70-80 80-90 > 90
14 Gy
3 iso-centers (2 gaps* 25.40 -
4 iso-centers (3 gaps) - 41.28 -
5 iso-centers (4 gaps) - 40.28 -
6 iso-centers (5 gaps) - 67.78 -
13 iso-centers (12 gaps) - 129.58
13 Gy
3 iso-centers (2 gaps) - 54.55 -
6 iso-centers (5 gaps) - 61.58 74.91 -
7 iso-centers (6 gaps) - 74.89 84.61 91.96
75.36 - 92.30
8 iso-centers (7 gaps) - 124.25
12 Gy
2 iso-centers (1 gap) 29.62 -
4 iso-centers (3 gaps) - 32.65 -
39.97
5 iso-centers (4 gaps) - 50.47 -
6 iso-centers (5 gaps) - 63.07 73.97 -
7 iso-centers (6 gaps) - 80.38
8 iso-centers (7 gaps) - 63.43 -
10 Gy
5 iso-centers (4 gaps) - 38.16 -
6 iso-centers (5 gaps) - 49.79
7 iso-centers (6 gaps) - 57.21 -
8 iso-centers (7 gaps) - 73.93 -
*

Nominal gap period 6 min.