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10J TSID concept
The curve indicates a total skull integral dose (TSID) of 10 Joules calculated using the GammaPlan, with 20Gy (50%) peripheral doses, for gamma knife (GK) stereotactic radiosurgery (SRS). Within these limits, we assume that 25 tiny, 10 small or 4 medium-sized lesions, if the tumors are approximately the same size and diffusely located, can be safely irradiated. This means that an almost 15 cm3 total tumor volume is the upper limit for safe GK-SRS.
