Supplemental Table 1.
Univariate and Multivariate Analysis for Overall Survival
| Univariate | Multivariate | |||||
| HR | 95% CI | p | HR | 95% CI | p-Value | |
| Age | 1.01 | 0.99-1.02 | 0.57 | - | - | - |
| Gender | 0.91 | 0.63-1.31 | 0.61 | - | - | - |
| Primary (v. Lung) | ||||||
| Breast | 0.58 | 0.37-0.91 | 0.02 | 0.59 | 0.38-0.92 | 0.02 |
| Melanoma | 1.32 | 0.77-2.26 | 0.31 | 1.36 | 0.79-2.36 | 0.27 |
| Other | 0.68 | 0.34-1.37 | 0.28 | 0.72 | 0.35-1.49 | 0.38 |
| Treatment Volume (cm3) | 0.94 | 0.64-1.36 | 0.73 | - | - | - |
| SRS Dose (Gy) | 0.95 | 0.89-1.01 | 0.10 | - | - | - |
| Any use of WBRT | 0.68 | 0.43-1.10 | 0.10 | - | - | - |
| Indication for SRS after WBRT (v. SRS alone) | ||||||
| WBRT LF | 1.12 | 0.67-1.89 | 0.66 | 1.18 | 0.69-1.99 | 0.55 |
| WBRT DF | 1.23 | 0.80-1.90 | 0.34 | 1.24 | 0.79-1.94 | 0.35 |
| Unknown | 0.87 | 0.44-1.70 | 0.68 | 0.97 | 0.49-1.95 | 0.94 |
| Time between WBRT and SRS (mo) | 0.96 | 0.94-0.99 | 0.005 | - | - | - |
HR: Hazard Ratio, CI: Confidence Interval, SRS: Stereotactic Radiosurgery, WBRT: Whole Brain Radiotherapy, cm3: cubic centimeter, Gy: Gray, mo: months, Other: RCC, colorectal, head & neck, genitourinary.