Table 1.
Patient and Treatment Characteristics by Treatment Paradigm.
| Total N (%) M (IQR) |
SRS Alone N (%) M (IQR) |
WBRT then SRS N (%) M (IQR) |
SRS then WBRT N (%) M (IQR) |
p-Value | |
| Age | 55 (48-63) | 56 (49-67) | 53 (47-61) | 59 (50-66) | 0.17 |
| Sex Male Female |
137 58 (42%) 79 (58%) |
32 16 (50%) 16 (50%) |
70 26 (37%) 44 (63%) |
35 16 (46%) 19 (54%) |
0.43 |
| Primary Tumor Lung Breast Melanoma Other |
137 69 (50%) 36 (26%) 21 (15%) 11 (8%) |
32 15 (47%) 7 (22%) 5 (16%) 5 (16%) |
70 37 (53%) 21 (30%) 11 (16%) 1 (1%) |
35 17 (49%) 8 (23%) 5 (14%) 5 (14%) |
0.19 |
| Metastases Per Patient | 2 (1-4) | 1 (1-2) | 3 (1-5) | 2 (1-3) | <0.001 |
| Total Metastases Treated | 411 | 51 (12%) | 275 (67%) | 85 (21%) | <0.001 |
| SRS Dose (Gy) | 19 (16-20) | 19 (18-21) | 18 (16-20) | 20 (18-21) | 0.006 |
| SRS Tumor Volume (cm3) | 0.35 (0.079-1.87) |
3.42 (0.28-5.62) |
0.26 (0.067-1.50) |
0.26 (0.061-1.34) |
<0.001 |
| WBRT Dose | 35 (30-37.5) |
- | 35 (30-37.5) |
31.3 (30.37.5) |
0.76 |
| Time between Treatment (mo) | 8.5 (4.8-13) |
- | 8.3 (5.5-13) |
8.7 (4.8-12.7) |
0.63 |
N: number, M: median, IQR: interquartile range, SRS: stereotactic radiosurgery, WBRT: whole brain radiotherapy, cm3: cubic centimeter, mo: months. Other: RCC, colorectal, head & neck, genitourinary.