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. 2017 Oct 26;16:430. doi: 10.1186/s12936-017-2074-7

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Determinants of in vivo response to anti-malarial treatment. ^a The process by which infected erythrocytes containing mature parasites adhere to the microvasculature. Their removal of from the circulation results in the peripheral parasite count being an underestimate of the true parasite biomass. ^b The developmental stage of the parasite. The artemisinin compounds have the broadest stage specific action against the parasite. ^c Simultaneous rupture of hepatic schizonts result in a uniform stage distribution of the parasite