Table 6.

Overview and comparison of significantly enriched gene sets in the model system and the patient plasma system^a

Gene sets enriched in Nm + IL-10 vs Nm	Gene sets enriched in patient plasma with IL-10 vs IL-10 immunodepleted plasma	Gene sets enriched in Nm vs Nm + IL-10	Gene sets enriched in IL-10 immunodepleted plasma vs patient plasma with with IL-10
Oxidative phosphorylation	Oxidative phosphorylation	TNF signaling	Interferon alpha response
MYC Targets_v1	Peroxisome	KRAS signaling DN	TNF signaling
DNA repair	MYC Targets_v1	Epithelial-mesenchymal transition	UV response
Adipogenesis	Adipogenesis	UV response	Interferon gamma response
Peroxisome	MYC targets_v2	Inflammatory response	Allograft rejection
MYC targets_v2	P53 Pathway	Kras signaling up	Kras signaling up
P53 Pathway	Reactive oxygen species	Apical surface	Hedgehog signaling
Protein secretion	DNA repair	Cholesterol homeostasis	Hallmark angiogenesis
	Fatty Acid Metabolism	Allograft rejection	Mitotic spindle
	Glycolysis	Interferon alpha response
	Bile acid metabolism	Coagulation

^aDetailed reports about the enriched gene sets is available in Additional files 4, 5, 6, 7